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Personalized modeling for drug concentration prediction using Support Vector Machine

机译:支持向量机的药物浓度预测个性化建模

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Building a personalized model to describe the drug concentration inside the human body for each patient is highly important to the clinical practice and demanding to the modeling tools. Instead of using traditional explicit methods, in this paper we propose a machine learning approach to describe the relation between the drug concentration and patients' features. Machine learning has been largely applied to analyze data in various domains, but it is still new to personalized medicine, especially dose individualization. We focus mainly on the prediction of the drug concentrations as well as the analysis of different features' influence. Models are built based on Support Vector Machine and the prediction results are compared with the traditional analytical models.
机译:建立个性化的模型来描述每个患者在人体内的药物浓度对临床实践和对建模工具的要求非常重要。代替使用传统的显式方法,在本文中,我们提出了一种机器学习方法来描述药物浓度和患者特征之间的关系。机器学习已被广​​泛应用于分析各个领域的数据,但是对于个性化医学(尤其是剂量个性化)而言,它仍然是新事物。我们主要集中在药物浓度的预测以及对不同特征影响的分析。基于支持向量机建立模型,并将预测结果与传统分析模型进行比较。

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