Instrumentation for in-vivo tissue spectroscopy and imaging

摘要

Abstract: cant progress has been made recently in techniques and corresponding instrumentation for optical spectroscopy and imaging of tissues in vivo, based on either optical absorption/scattering, fluorescence, or Raman effects. The focus of this paper is on the principles and instrumentation required for in vivo use, particularly non-invasive clinical applications. Progress in absorption spectroscopy and imaging are emphasized in order to illustrate principles and some of the major limitations of current technologies. Possible future approaches to practical clinical instrumentation are indicated. !50