Transport, transformation and fate of endocrine disruptors: potential areas of exposure research

摘要

A growing number of studies suggest that several persistent orgajic pollutants and some organic forms of heavy metals, such as those listed recently by the Inter-Organizational Program for the Sound Management of Chemicals, appear to mimic or to disrupt hormonal mechanisms in humans and wildlife. EPA is exploring methods and models to measure and to predict exosures to these substances. This paper addresses a number of approaches the Agency may take to conduct exposure research of endocrine disrupting compounds within the Agency's risk assessment framework.