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IDENTIFICATION OF REGULATORY PATHWAYS OF THE CELL CYCLE IN FISSION YEAST

机译:裂殖酵母细胞周期调控途径的鉴定

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摘要

A novel identification method is presented, aimed at the reconstruction of genetic network structures. The iterative identification algorithm is based on least square linear regression, tailored to the case of scale free networks. The devised technique is assessed by comparing identification results with a well established in silico model of fission yeast cell cycle. Finally it is exploited for identifying the genetic network of fission yeast from experimental data available in the literature.
机译:提出了一种新颖的识别方法,旨在重建遗传网络结构。迭代识别算法基于最小平方线性回归,适合无标度网络的情况。通过将鉴定结果与成熟的裂变酵母细胞周期的计算机模拟模型进行比较,可以评估所设计的技术。最后,它可用于从文献中获得的实验数据中鉴定裂变酵母的遗传网络。

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