Sealed hollow waveguide for catheter-based pulsed photodynamic therapy

摘要

Sealed hollow waveguides have been used to transmit nanosecond red light pulses for photodynamic therapy. With a 1-mm inner diameter, 1-m long, COP (cyclic olefin polymer)-coated silver hollow waveguide, available transmitted pulse energy exceeded 15 mJ, the corresponding peak power and intensity at the output window being 3 MW and 380 MW/cm~2 respectively. Because the diameter of the window was as small as 1.5 mm, the waveguide can be introduced to catheters.