Mathematical mass transfer model of racemic resolution for chiral compounds using HFSLM was presented in this study. Factors such as transportation resistance of boundary layers in strip phase inside the hollow fiber and in feed phase on the shell side of the hollow fiber module, diffusion resistance in the membrane solution and equilibrium constant of interfacial chemical reactions are considered in this mathematical model. The validity of the model is tested by resolution of D, L-phenylalanine with HFSLM using CuN2 as chiral carrier dissolved in a organic solvent (hexanol :decane, 1:1). Using experimental results, several parameters of the proposed model have been achieved by nonlinear fitting method.
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